READD-ADSP: Building a Genetic Resource to Understand Alzheimer’s in African and Hispanic/Latino Communities
Official title: Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
Funded at University of Miami School of Medicine · NIH-11563837 · Data updated 2026-11-12
A big, shared genetic resource is being created to study why Alzheimer’s disease affects people of African and Hispanic/Latino ancestry differently.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $59,534 |
| NIH project number | 3U19AG074865-05S8 |
| Project ID | NIH-11563837 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals of African, African American, or Hispanic/Latino ancestry, aged at risk for or affected by Alzheimer’s disease or related dementias.
✕Less likely to help
Participants outside the targeted ancestry groups or those not contributing phenotypic/genetic data may not directly benefit.
What this research studies
This project plans to recruit and genotype about 13,000 individuals from diverse ancestries to study the genetic factors that influence Alzheimer’s risk. It will harmonize clinical, phenotypic, and genetic data with existing AD genomics efforts to enable broader, more powerful analyses. Two hypothesis-driven projects will use the resource to explore how ancestry and environment interact to affect disease risk and progression.
Why it matters
Potential benefit: If successful, the resource could reveal new genetic risk factors and help tailor prevention and treatment approaches for diverse populations.
How similar studies have gone: Previous large-scale AD genomics efforts have identified ancestry-specific risk factors, and expanding diversity is a growing, promising area.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.