READD-ADSP: Building a Genetic Resource to Understand Alzheimer's in African and Hispanic/Latino Populations
Official title: Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
Funded at University of Miami School of Medicine · NIH-11563827 · Data updated 2026-11-12
A large, patient-focused genetic program aims to create a shared resource to study Alzheimer’s disease in African, African American, and Hispanic/Latino communities to improve understanding of risk and biology.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $44,055 |
| NIH project number | 3U19AG074865-05S6 |
| Project ID | NIH-11563827 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults of African, African American, or Hispanic/Latino ancestry who are part of or at risk for Alzheimer’s disease or related dementias.
✕Less likely to help
Individuals without these ancestries or with no interest in genetic contributions to dementia may not directly benefit.
What this research studies
This project will recruit and collect data from about 13,000 individuals across Africa, African Americans, and Hispanic/Latino groups, then genotype and harmonize clinical and genetic information with existing AD datasets. By comparing genetic risk factors across diverse populations, researchers hope to reveal how ancestry and environment interact to influence Alzheimer's risk. The effort includes two hypothesis-driven projects to demonstrate how this resource can advance our knowledge and future studies. The work will involve collaboration with international sites and existing AD genomics consortia to share data and tools for broad scientific use.
Why it matters
Potential benefit: If successful, the resource could lead to more accurate risk prediction and new targets for prevention or treatment tailored to diverse populations.
How similar studies have gone: Previous AD genetics projects have shown that diverse populations improve discovery of risk factors and biological pathways.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.