READD-ADSP: Building a diverse genetic resource to understand Alzheimer’s in African and Hispanic/Latino populations
Official title: Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
Funded at University of Miami School of Medicine · NIH-11563834 · Data updated 2026-11-12
A large, patient-focused genetics project will recruit and study 13,000 people to understand how genes and ancestry affect Alzheimer’s risk across diverse populations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $63,323 |
| NIH project number | 3U19AG074865-05S7 |
| Project ID | NIH-11563834 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults of African, African American, or Hispanic/Latino ancestry who can participate in genetic research and clinical assessments.
✕Less likely to help
Individuals who prefer not to share genetic or health information or who do not represent these ancestries may not directly benefit.
What this research studies
This program creates a big, internationally diverse resource to study the genetic factors behind Alzheimer’s by collecting clinical, phenotypic, and DNA data from people with African and Hispanic/Latino ancestry, and harmonizing it with existing datasets. It includes two hypothesis-driven projects to show how this resource can help uncover ancestry-related risk factors and improve our understanding of AD biology. Researchers will recruit participants, collect biospecimens, genotype samples, and integrate data so that later studies can explore genetic influences on AD across populations. The project aims to illuminate why Alzheimer’s risk and biomarker patterns differ by ancestry and how these insights could guide future prevention or treatment efforts.
Why it matters
Potential benefit: If successful, this resource could lead to more accurate risk assessments and tailored prevention strategies for diverse populations.
How similar studies have gone: Previous large consortium efforts have begun to map ancestry-related AD risk, with ongoing work showing promise in diverse populations.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.