READD-ADSP: Building a big genetic resource to study Alzheimer’s in diverse populations
Official title: Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
Funded at University of Miami School of Medicine · NIH-11563818 · Data updated 2026-11-12
A large research effort aims to create a shared genetic resource to understand how Alzheimer’s disease affects people of African and Hispanic/Latino ancestry and how genetic factors like APOE influence risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $48,665 |
| NIH project number | 3U19AG074865-05S1 |
| Project ID | NIH-11563818 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals of African, African American, or Hispanic/Latino ancestry who may later participate in genetic studies or related research.
✕Less likely to help
People who do not identify with these ancestries or are not invited to participate in genetic research may not benefit directly.
What this research studies
This project will recruit and collect data from 13,000 individuals across Africa, African Americans, and Hispanic/Latino groups, then genotype and harmonize clinical and genetic information with existing AD studies. The resulting resource will help researchers examine how ancestry and environment shape Alzheimer’s risk and disease biology. Two hypothesis-driven projects will use the resource to illustrate its value and advance knowledge about genetic contributions to Alzheimer’s in underrepresented populations.
Why it matters
Potential benefit: If successful, the resource could lead to more accurate risk prediction and better-tailored approaches for prevention and treatment in diverse populations.
How similar studies have gone: Previous large-scale AD genomics efforts have shown that diverse datasets improve discovery and understanding of risk factors.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.