NIH-funded research R01 grant

Radon Exposure and Stroke: How a Home Gas Might Influence Brain Vascular Health

Official title: The Epidemiology and Somatic Genomic Pathogenesis of Radon-Related Stroke

Funded at Univ of North Carolina Chapel Hill · NIH-11590631 · Data updated 2026-11-12

This project looks at whether radon exposure in homes is linked to stroke risk and brain vascular problems in people across the United States.

More Stroke research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 11, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$671,367
NIH project number4R01ES034050-02
Project IDNIH-11590631 on NIH RePORTER

Who could benefit from this research

Could help

Adults across the United States who live in homes with measurable radon exposure and have or are at risk for cerebrovascular disease.

Less likely to help

People without exposure data or those not at risk for stroke may see limited direct benefit.

What this research studies

Stroke is a leading cause of disability and death, and many strokes occur without a clear cause. This study will map home radon levels from 1986 to 2018 and examine how changes in radon exposure relate to the development of stroke and its precursors. Researchers will combine environmental data with health records to explore links between radon and brain vascular disease, aiming to identify potential prevention opportunities. The findings could inform public health recommendations to reduce radon exposure and protect brain health.

Why it matters

Potential benefit: If successful, the work could lead to better strategies to prevent stroke by reducing radon exposure in homes.

How similar studies have gone: Prior studies suggest a possible link between radon and cerebrovascular outcomes, but comprehensive nationwide analyses are still needed, making this work a significant step forward.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Whitsel, Eric a. — Univ of North Carolina Chapel Hill
  • Study coordinator: Whitsel, Eric a.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.