Quick testing for antibiotic resistance in bacteria from blood samples
Rapid Antibiotic Susceptibility Testing via Selective Lysis and Nanogap Trapping
This study is working on a quick way to test how bacteria in your blood react to antibiotics, so doctors can make faster and better treatment decisions when you're sick.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Maryland, College Park NIH-funded |
| Lab location | 1 site (College Park, United States) |
| Project ID | NIH-11110065 on NIH RePORTER |
What this research studies
This research aims to develop a rapid method for testing how bacteria respond to antibiotics directly from blood samples. By using a microfluidic technology, the project will isolate bacteria from blood, identify the pathogens, and assess their susceptibility to antibiotics within 75 minutes. This approach seeks to overcome the limitations of current testing methods that are often too slow for timely treatment decisions, especially during critical early stages of infection. The goal is to provide clinicians with faster and more accurate information to guide antibiotic therapy, ultimately improving patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients presenting with acute bacterial infections who require timely antibiotic treatment.
Not a fit: Patients with viral infections or those who do not require antibiotic therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective treatment of bacterial infections, reducing complications and healthcare costs associated with antibiotic resistance.
How similar studies have performed: Other research has shown promise in rapid antibiotic susceptibility testing, but this specific approach using microfluidic technology is relatively novel.
Where this research is happening
College Park, United States
- Univ of Maryland, College Park — College Park, United States (Active)
Researchers
- Principal investigator: Devoe, Don L — Univ of Maryland, College Park
- Study coordinator: Devoe, Don L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.