Quantitative Imaging of Brain Physiological Markers
Official title: TRD 1: Quantitative Imaging of Physiological Markers
Funded at Hugo W. Moser Res Inst Kennedy Krieger · NIH-11334984 · Data updated 2026-11-12
A research project using advanced brain MRI to measure biological markers that could help doctors pick the right treatments and monitor outcomes for people with brain-related conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hugo W. Moser Res Inst Kennedy Krieger NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $163,242 |
| NIH project number | 2P41EB031771-06 |
| Project ID | NIH-11334984 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with brain conditions that would benefit from advanced imaging biomarkers and treatment monitoring.
✕Less likely to help
Individuals without brain disorders or those not undergoing MRI-based biomarker assessment may not directly benefit.
What this research studies
This grant supports developing and refining MRI techniques that quantify brain physiology beyond simple images. It aims to create biomarkers from physiological MRI that can help in diagnosing diseases and tracking how well treatments work. The work will explore brain fluid circulation and barrier function, including new imaging methods that may or may not use contrast agents. Researchers will work on specific aims to advance non-contrast and contrast-enhanced MRI techniques to measure brain physiology.
Why it matters
Potential benefit: If successful, patients could benefit from more precise biomarkers that guide diagnosis and treatment decisions in brain diseases.
How similar studies have gone: Previous work in physiological MRI has shown promise in biomarker development for brain diseases, with ongoing interest from the neuroscience community.
Where this research is happening
-
Hugo W. Moser Res Inst Kennedy Krieger
Baltimore, United States Active
Researchers
- Principal investigator: Lu, Hanzhang — Hugo W. Moser Res Inst Kennedy Krieger
- Study coordinator: Lu, Hanzhang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.