NIH-funded research NIH-funded research

Promoting Retention in Opioid Treatment for Women Experiencing Intimate Partner Violence with PTSD

Official title: Promoting Retention in Opioid Treatment among Women Experiencing Intimate Partner Violence: A Novel Stepped Care Model Targeting PTSD

Funded at Yale University · NIH-11419015 · Data updated 2026-11-12

A new stepped-care approach helps women on opioid treatment who experience ongoing IPV and PTSD stay in treatment longer and feel better.

More PTSD research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 30, 2023
Project endAugust 31, 2029
Funding year2026
Award (this year)$885,992
NIH project number5R33DA059895-03
Project IDNIH-11419015 on NIH RePORTER

Who could benefit from this research

Could help

Women with opioid use disorder who are experiencing intimate partner violence and have PTSD-related impairment, receiving or eligible for MOUD treatment.

Less likely to help

Individuals without IPV or PTSD or those not engaged in MOUD treatment may derive less benefit.

What this research studies

This project adapts proven PTSD-focused therapies for women facing ongoing IPV while receiving medication for opioid use disorder. It uses a stepped-care model to deliver Present-Centered Therapy+ (PCT+) and HOPE in MOUD settings, starting with accessible treatment and escalating as needed. The goal is to reduce PTSD-related impairment and improve MOUD retention by addressing current stressors and trauma in a safe, supportive way. Treatments are designed to be delivered by nonclinical staff or Master’s level therapists within real-world clinics. The study will measure PTSD symptoms, functioning, and treatment adherence to determine if the approach improves outcomes for women with co-occurring OUD, IPV, and PTSD.

Why it matters

Potential benefit: If successful, patients could experience fewer PTSD symptoms, better daily functioning, and higher retention in opioid treatment.

How similar studies have gone: Evidence-based, manualized interventions (PCT+ and HOPE) exist for this population, and integrating them into MOUD settings is a novel application.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Sullivan, Tami P — Yale University
  • Study coordinator: Sullivan, Tami P

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.