Promoting diabetes screening to improve health outcomes
Official title: Promoting Uptake of Evidence-Based DiaBetes and Prediabetes Screening to Increase HeaLth Effectiveness Study (PEBBLES)
Funded at University of California Los Angeles · NIH-11364689 · Data updated 2026-11-12
A study tests different messaging and outreach methods to encourage adults aged 35-70 with overweight or obesity to get screened for type 2 diabetes and prediabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | June 5, 2026 |
| Project end | April 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $751,436 |
| NIH project number | 1R01DK142813-01A1 |
| Project ID | NIH-11364689 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 35-70 with overweight or obesity (BMI > 25) who are patients within participating health systems and are reachable by text, portal, or mail.
✕Less likely to help
Individuals who are not receptive to screening messaging or who do not have access to the outreach modalities may see limited benefit.
What this research studies
This project will develop and test outreach messages delivered by text, patient portal, or mailed letters to encourage timely screening for diabetes and prediabetes. It uses an adaptive SMART design to tailor the approach based on how people respond to initial messaging. By engaging diverse communities and co-designing materials, the study aims to find effective, scalable ways to increase screening uptake and connect people to prevention programs.
Why it matters
Potential benefit: If successful, it could lead to more people being screened earlier and receiving preventive care to reduce diabetes risk.
How similar studies have gone: Previous work shows messaging strategies can influence screening uptake, but this SMART-design study explores adaptive, multi-modal approaches.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Duru, Obidiugwu Kenrik — University of California Los Angeles
- Study coordinator: Duru, Obidiugwu Kenrik
Related research
Other NIH-funded projects on the same topics.
-
Alzheimer’s and dementia risk in people with prediabetes or type 2 diabetes
This grant aims to understand why some older adults with prediabetes or type 2 diabetes develop memory problems or dementia.
-
Alzheimer’s and related dementia in older adults with prediabetes or type 2 diabetes
This grant aims to understand why cognitive problems occur in people 65 and older who have prediabetes or type 2 diabetes, using data from a long-running diabetes study to identify what drives memory and thinking decline.
-
Effects of different exercise intensities on blood vessels and metabolism in prediabetes and diabetes
This project tests how moderate and high-intensity interval exercise affects blood vessel and fat tissue function in male and female rats with prediabetes or diabetes.
-
ONWARD: Helping teens and young adults with prediabetes and type 2 diabetes get the resources they need
A study tests easy, in-clinic and post-visit resource help for teens and young adults with type 2 diabetes to address social needs that affect their health.
-
Alzheimer's and related dementia risk in people with prediabetes and type 2 diabetes
This project looks at brain changes, memory, medications, and health measures in older adults with prediabetes or type 2 diabetes to find what leads to dementia.
-
Smartphone and smartwatch screening for prediabetes and type 2 diabetes
This project uses data from smartphones and smartwatches to spot early signs of prediabetes and type 2 diabetes in adults who have no symptoms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.