Prevention of Amputation with Rapid Healing of Diabetic Ulcers Using a Patient's Own Fat
Official title: Prevention of Amputation with Rapid Healing of Diabetic Ulcers Using Autologous Microsized Fat Tissue
Funded at Syntr Health Technologies, LLC · NIH-11349024 · Data updated 2026-11-12
A new, quick, point-of-care treatment using a patient’s own fat tissue aims to speed healing of foot ulcers in adults with diabetes to prevent amputation.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Syntr Health Technologies, LLC NIH-funded |
| Lab location | 1 site (Irvine, UNITED STATES) |
| Project start | September 22, 2026 |
| Project end | September 21, 2027 |
| Funding year | 2026 |
| Award (this year) | $313,372 |
| NIH project number | 1R43DK147508-01 |
| Project ID | NIH-11349024 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with diabetes who have foot ulcers and are eligible for the SyntrFuge™ System intervention.
✕Less likely to help
Patients with ulcers not responding to autologous fat treatment or with contraindications may not benefit.
What this research studies
This project aims to help adults with diabetes who have diabetic foot ulcers by using autologous fat tissue processed at the point of care to promote faster healing. The approach leverages a system that harvests and prepares a patient’s fat tissue during the visit and applies it to the wound. If successful, this could reduce the need for amputations and lower healthcare costs tied to DFUs. The study focuses on patients treated in a real-world clinical setting and tracks healing outcomes and safety.
Why it matters
Potential benefit: If successful, patients could see faster wound healing and a lower risk of amputation.
How similar studies have gone: There is ongoing interest in autologous fat-based therapies for wound healing, with mixed but promising early results.
Where this research is happening
-
Syntr Health Technologies, LLC
Irvine, United States Active
Researchers
- Principal investigator: Zobi, Ahmed Nabil — Syntr Health Technologies, LLC
- Study coordinator: Zobi, Ahmed Nabil
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.