NIH-funded research NIH-funded research

Prefrontal Brain Development and Adolescent Reward-Seeking Behavior

Official title: Implications of Prefrontal Cortex Development for Adolescent Reward Seeking Behavior

Funded at State University of Ny,binghamton · NIH-11418518 · Data updated 2026-11-12

A young-person study explores how changing brain circuits during adolescence influence impulse control and reward-driven behaviors.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionState University of Ny,binghamton
NIH-funded
Lab location1 site (Binghamton, United States)
Project startAugust 1, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$224,099
NIH project number5R00MH132082-04
Project IDNIH-11418518 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents and young adults experiencing anxiety disorders or related behavioral challenges.

Less likely to help

The study may not directly benefit individuals outside the adolescent age range or without anxiety-related concerns.

What this research studies

This project looks at how growth in the brain’s decision-making area (the mPFC) and the feeding/drive area (the LH) during adolescence may shape impulsivity and reward-seeking. Researchers plan to study these brain regions and their communication to understand why teens often act on rewards and face behavioral switching challenges. The work will involve brain imaging and possibly other measures to connect brain changes with typical adolescent behavior, with a focus on anxiety-related concerns. The goal is to map how adolescent brain development could underlie risky or reward-driven choices, which could inform future strategies for youth well-being.

Why it matters

Potential benefit: If successful, findings could inform better approaches to support adolescents in managing impulses and rewards, potentially reducing anxiety-related challenges.

How similar studies have gone: Previous work has linked mPFC and LH development to reward processing, but detailed adolescent circuit dynamics remain an active area with promising but early results.

Where this research is happening

  • State University of Ny,binghamton
    Binghamton, United States
    Active

Researchers

  • Principal investigator: Manzano Nieves, Gabriela — State University of Ny,binghamton
  • Study coordinator: Manzano Nieves, Gabriela

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.