Chemical methods to control RNA function in cells
Official title: Chemical Approaches to Control the Function of Regulatory RNAs
Funded at State University of Ny,binghamton · NIH-11527837 · Data updated 2026-11-12
A scientist-led project explores new chemical tweaks to how regulatory RNAs work, with potential implications for biology and medicine.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of Ny,binghamton NIH-funded |
| Lab location | 1 site (Binghamton, United States) |
| Project start | June 1, 2019 |
| Project end | January 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $163,912 |
| NIH project number | 3R35GM130207-08S1 |
| Project ID | NIH-11527837 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to patients directly, but the research could inform future RNA-targeted therapies for various diseases.
✕Less likely to help
Direct patient benefit is unlikely during early development; immediate clinical impact is not guaranteed.
What this research studies
This work focuses on designing chemical modifications to RNA to change its shape and activity. It includes two main parts: improving RNA backbone linkages for better specificity, and using modified peptide nucleic acids to influence RNA structure and function. The goal is to create tools that help scientists study RNA behavior and potentially guide future therapeutic approaches. The program combines foundational chemistry with concepts that could impact how we manipulate RNA in research and medicine.
Why it matters
Potential benefit: If successful, it could provide new RNA-based tools and strategies that advance biomedical research and precision therapies.
How similar studies have gone: Previous RNA modification efforts have shown promise in modulating RNA function, supporting continued exploration in this area.
Where this research is happening
-
State University of Ny,binghamton
Binghamton, United States Active
Researchers
- Principal investigator: Rozners, Eriks — State University of Ny,binghamton
- Study coordinator: Rozners, Eriks
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.