NIH-funded research Career grant

Preference-based value of thyroid cancer treatments for small tumors

Official title: Preference-Based Treatment Valuation in Low-Risk Thyroid Cancer

Funded at University of Maryland Baltimore · NIH-11369995 · Data updated 2026-11-12

This grant asks how patients feel about different PTMC treatments (watchful waiting, partial/total thyroidectomy, or radiofrequency ablation) and how those feelings affect overall care decisions.

More Thyroid Cancer research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore
NIH-funded
Lab location1 site (Baltimore, United States)
Project startJuly 17, 2024
Project endJune 30, 2028
Funding year2026
Award (this year)$284,358
NIH project number5K08CA293167-03
Project IDNIH-11369995 on NIH RePORTER

Who could benefit from this research

Could help

Adults with low-risk, sub-centimeter papillary thyroid microcarcinoma (PTMC) considering active surveillance or treatment options.

Less likely to help

Patients not facing thyroid cancer or those not involved in decision-making about treatment options are unlikely to benefit.

What this research studies

For adults with very small, low-risk thyroid cancer, researchers will measure how people value different treatment experiences using patient-friendly questions. The project will compare feelings about surveillance, surgery, and energy-based ablation to create a clearer picture of which options patients prefer beyond survival. Findings will be used in a cost-effectiveness model to help doctors and patients choose the approach that aligns with patient values and real-world experiences. The work will involve discussions with patients, clinicians, and the general public to determine whose perspectives best reflect treatment value.

Why it matters

Potential benefit: If successful, the study could help doctors and patients choose treatments that better align with patient preferences and reduce unnecessary morbidity and costs.

How similar studies have gone: There is limited data on health-state utilities in PTMC; this project aims to fill that gap with primary preference data.

Where this research is happening

  • University of Maryland Baltimore
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Hu, Yinin — University of Maryland Baltimore
  • Study coordinator: Hu, Yinin

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.