NIH-funded research NIH-funded research

Predictors of Opioid Use Disorder and Overdose in Post-9/11 Veterans

Official title: Predictor Profiles of Opioid Use Disorders and Overdose Among Post-9/11 Veterans

Funded at VA Boston Health Care System · NIH-11285199 · Data updated 2026-11-12

A study using machine learning to find factors that raise the risk of opioid use disorder and overdose in Post-9/11 veterans, and to understand how COVID-19 may affect that risk.

More Opioid Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Boston Health Care System
NIH-funded
Lab location1 site (Boston, United States)
Project startApril 1, 2022
Project endMarch 31, 2027
Funding year2026
NIH project number5IK2CX002192-05
Project IDNIH-11285199 on NIH RePORTER

Who could benefit from this research

Could help

Post-9/11 veterans who have access to VA care and whose data are available for analysis.

Less likely to help

Veterans without identified risk factors or those not accessing VA care may see limited direct benefit.

What this research studies

This project will analyze health and psychosocial data from veterans to identify how different risks combine to influence opioid use and overdose. It uses advanced computer models to examine many factors, including medical history, mental health, trauma exposure, and social determinants. The goal is to produce actionable insights that clinicians and caregivers can use to prevent OUD and overdose in veterans, especially in the context of the COVID-19 era.

Why it matters

Potential benefit: If successful, findings could help tailor prevention and early intervention strategies for veterans at high risk of opioid misuse and overdose.

How similar studies have gone: Previous studies using machine learning have shown promise in predicting risk, with this project aiming to extend that work to veterans and pandemic-related factors.

Where this research is happening

  • VA Boston Health Care System
    Boston, United States
    Active

Researchers

  • Principal investigator: Fonda, Jennifer R — VA Boston Health Care System
  • Study coordinator: Fonda, Jennifer R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.