Predicting heart problems in breast cancer patients using an AI system
Official title: Treatment-Related Cardiotoxicity Risk Prediction for Breast Cancer Patients with a Multimodal AI-based System
Funded at Ohio State University · NIH-11360214 · Data updated 2026-11-12
A multimodal AI system will help doctors predict who may develop heart-related side effects during or after breast cancer treatment and guide safer therapy choices.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | June 23, 2025 |
| Project end | May 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $641,078 |
| NIH project number | 5R01CA301579-02 |
| Project ID | NIH-11360214 on NIH RePORTER |
Who could benefit from this research
✓Could help
Breast cancer patients undergoing treatment with therapies known to affect the heart, such as anthracyclines or biologics/immunotherapy.
✕Less likely to help
Patients not receiving cardiotoxic cancer therapies or those without available electronic health data may not benefit.
What this research studies
This project uses artificial intelligence to analyze patients’ health records and other data to forecast who is at risk of serious heart problems during breast cancer treatment. By identifying risk early, clinicians can adjust cancer therapies or add heart-protective steps to reduce cardiovascular events. The effort combines data from past patients and real-time information to improve prediction accuracy while addressing how best to apply AI in a clinical setting. The goal is to support personalized treatment plans that balance cancer control with heart health.
Why it matters
Potential benefit: If successful, the AI tool could help doctors tailor cancer therapy to minimize heart damage and improve long-term health for breast cancer patients.
How similar studies have gone: Early AI-based risk models have shown promise but often struggle with generalization in real-world practice.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Cao, Weidan — Ohio State University
- Study coordinator: Cao, Weidan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.