NIH-funded research R01 grant

Precision skin cancer risk feedback in community clinics

Official title: A hybrid effectiveness-implementation trial to integrate precision skin cancer risk feedback in federally qualified health centers

Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11391189 · Data updated 2026-11-12

A multisite study tests giving adults personalized genetic risk information to boost sun protection and skin checks in low-resource primary care settings.

More Skin Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionH. Lee Moffitt Cancer Ctr & Res Inst
NIH-funded
Lab location1 site (Tampa, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2029
Funding year2026
Award (this year)$2,037,289
NIH project number4R01CA291735-03
Project IDNIH-11391189 on NIH RePORTER

Who could benefit from this research

Could help

Adults (21+ years) seeking care at participating low-resource community primary care clinics who are offered the personalized risk feedback.

Less likely to help

Some individuals may not change prevention behaviors despite receiving personalized information.

What this research studies

This project will test a precision prevention approach that shares genetically informed skin cancer risk with adults visiting community clinics. It uses a hybrid type 1 design to measure real-world effectiveness while studying how best to implement the approach in busy, under-resourced primary care. Participants will be adults of any race/ethnicity who receive tailored educational materials in English or Spanish and are followed to see if prevention behaviors improve. The study also looks at barriers and facilitators to putting the intervention into routine practice so it can be scaled up if successful. Outcomes include changes in sun protection, skin examinations, and overall adoption in community clinics.

Why it matters

Potential benefit: If successful, patients could receive personalized guidance to reduce skin cancer risk and improve early detection through routine care in community clinics.

How similar studies have gone: Previous trials showed improvements in prevention behaviors and acceptable materials in English and Spanish, with promising reach and engagement.

Where this research is happening

  • H. Lee Moffitt Cancer Ctr & Res Inst
    Tampa, United States
    Active

Researchers

  • Principal investigator: Kanetsky, Peter a — H. Lee Moffitt Cancer Ctr & Res Inst
  • Study coordinator: Kanetsky, Peter a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.