Postmenopausal androgens and heart risk in aging women
Official title: Postmenopausal androgens, sex hormone binding globulin, and cardiovascular risk: a cohort study
Funded at Kaiser Foundation Research Institute · NIH-11365488 · Data updated 2026-11-12
A funded project will study how hormones after menopause relate to heart disease risk in aging women.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | July 15, 2026 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,758,740 |
| NIH project number | 1R01HL180757-01A1 |
| Project ID | NIH-11365488 on NIH RePORTER |
Who could benefit from this research
✓Could help
Older women who are participants in the Women’s Health Initiative with stored biospecimens and longitudinal CV risk data.
✕Less likely to help
Women without access to WHI data or without stored biospecimens will not directly benefit from this ancillary study.
What this research studies
This project will follow women who are part of a long-running study to see how levels of hormones like testosterone and related proteins change over 20–30 years and how those changes relate to heart disease risk markers. Researchers will use stored blood samples and existing data from the Women’s Health Initiative to track patterns in postmenopausal androgens and SHBG over time. The goal is to identify hormone profiles that accompany higher or lower cardiovascular risk, which could inform future prevention and treatment strategies. This work is done through an ancillary study that leverages existing resources to deepen our understanding of hormone-related cardiovascular risk in older women.
Why it matters
Potential benefit: If successful, the findings could help tailor cardiovascular risk assessment and prevention for postmenopausal women based on hormonal profiles.
How similar studies have gone: This type of longitudinal analysis builds on prior work but remains to be proven in its ability to predict CV risk based on postmenopausal androgens.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Harrington, Laura Brienne — Kaiser Foundation Research Institute
- Study coordinator: Harrington, Laura Brienne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.