NIH-funded research R01 grant

Population-wide deep learning glaucoma screening Models

Official title: Developing Population-Generalizable Deep Learning Models for Automated Glaucoma Screening

Funded at Schepens Eye Research Institute · NIH-11419231 · Data updated 2026-11-12

Aims to create AI eye-screening tools that work well for diverse populations so people can get easy glaucoma checks from primary care or pharmacies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSchepens Eye Research Institute
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 30, 2024
Project endJuly 31, 2029
Funding year2026
Award (this year)$680,583
NIH project number5R01EY036222-03
Project IDNIH-11419231 on NIH RePORTER

Who could benefit from this research

Could help

Individuals at risk for glaucoma or those with limited access to eye care who could benefit from screening in non-specialist settings.

Less likely to help

Patients who already receive regular comprehensive eye exams may not directly benefit from a screening tool.

What this research studies

This project develops deep learning models that use retinal images to detect glaucoma and tests how well they generalize across different populations. It uses optical coherence tomography and fundus photos, with new metrics that measure consistency of performance across groups. The goal is a reliable screening tool that can be deployed in primary care and accessible settings, reducing undiagnosed glaucoma.

Why it matters

Potential benefit: If successful, the tool could enable widespread, accessible glaucoma screening and earlier detection, potentially preventing vision loss.

How similar studies have gone: Past studies show promise for deep learning in glaucoma detection, but generalizability across diverse populations remains a challenge.

Where this research is happening

  • Schepens Eye Research Institute
    Boston, United States
    Active

Researchers

  • Principal investigator: Wang, Mengyu — Schepens Eye Research Institute
  • Study coordinator: Wang, Mengyu

Related research

Other NIH-funded projects on the same topics.

  • AI screening that detects glaucoma across diverse populations

    This project builds AI that reads retinal photos and OCT scans to find glaucoma early for people from different racial and ethnic backgrounds.

    NIH research Schepens Eye Research Institute · Boston, United States · NIH-11184318

  • Finding Glaucoma Vision Loss Early with Computer Learning

    This project uses advanced computer learning to help doctors find vision changes in glaucoma patients sooner, especially for veterans.

    NIH research Iowa City VA Medical Center · Iowa City, United States · NIH-11092687

  • Using deep learning to detect and predict glaucoma progression from eye scans

    This study is looking at how we can better spot and track primary open angle glaucoma using advanced computer technology, so that patients can get the help they need sooner and manage their condition more effectively.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11081725

  • Creating fair AI models for glaucoma screening

    This study is working on using smart computer technology to help find glaucoma early, especially for people from different backgrounds who might not have easy access to eye care, so that everyone can get the right diagnosis without needing expensive specialist visits.

    NIH research Schepens Eye Research Institute · Boston, United States · NIH-10872671

  • IOP and CSF Pressure in Glaucoma Risk

    This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11644421

  • Integrative histo-genomic analysis to guide cancer risk and targeted therapies with interpretable AI

    Researchers are developing an advanced AI-powered approach to map genetic and cellular patterns across breast and cervical cancers to help tailor treatments.

    NIH research Tuskegee University · Tuskegee Institute, United States · NIH-11621787

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.