Personalizing Follow-Up After Colorectal Polyps to Prevent Cancer
Official title: Personalizing Post-Polypectomy Surveillance for Colorectal Cancer Prevention
Funded at Kaiser Foundation Research Institute · NIH-11416487 · Data updated 2026-11-12
Aims to tailor post-polypectomy follow-up so people who had precancerous polyps avoid unnecessary procedures while catching cancer early.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | September 19, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $646,357 |
| NIH project number | 5R37CA276306-04 |
| Project ID | NIH-11416487 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who have had at least one precancerous polyp removed during CRC screening and are awaiting surveillance decisions.
✕Less likely to help
Patients with very low risk may not see significant changes to their follow-up plan.
What this research studies
This project focuses on improving surveillance after a polyp is removed during colorectal cancer screening. It combines clinical data and genetic risk factors to create a practical plan for how often patients should have follow-up colonoscopies. The team will develop and test risk-based guidance that goes beyond current guidelines to better balance benefits and harms for individuals. If successful, it could mean fewer unnecessary procedures for many and earlier detection for those at higher risk.
Why it matters
Potential benefit: Patients could receive more personalized follow-up schedules, potentially reducing unnecessary colonoscopies and improving early detection of cancer.
How similar studies have gone: Previous research suggests polyp characteristics alone are limited for guiding surveillance, and incorporating genetic risk may improve prediction.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Lee, Jeffrey Kuang Zou — Kaiser Foundation Research Institute
- Study coordinator: Lee, Jeffrey Kuang Zou
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.