NIH-funded research R01 grant

Personalized blood pressure goals for people with HFpEF

Official title: Precision Blood Pressure Goals in Patients with Heart Failure with Preserved Ejection Fraction: A HeartShare Ancillary Study

Funded at Northwestern University · NIH-11279912 · Data updated 2026-11-12

A big study will look at how to best manage blood pressure for adults with heart failure with preserved ejection fraction to help reduce hospitalizations and improve survival.

More Heart Failure research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 15, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$719,141
NIH project number1R01HL183589-01
Project IDNIH-11279912 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 21 and older with HFpEF who have hypertension and are managed with anti-hypertensive therapies.

Less likely to help

Patients without HFpEF or without hypertension may not benefit from the findings.

What this research studies

This project uses an AI-based approach to analyze real-world data on blood pressure, treatments, and outcomes in adults with HFpEF. It aims to identify how different BP targets affect health, recognizing that a single goal may not fit every patient. Researchers will examine patterns over time to see which factors modify the ideal BP, including comorbidities and treatment histories. The goal is to inform personalized BP management strategies for HFpEF patients.

Why it matters

Potential benefit: If successful, patients with HFpEF could receive more tailored blood pressure targets that reduce complications and improve quality of life.

How similar studies have gone: Previous large trials informed general BP targets, but this study focuses on HFpEF with personalized goals, which is a newer, data-driven approach.

Where this research is happening

  • Northwestern University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Ahmad, Faraz Shafique — Northwestern University
  • Study coordinator: Ahmad, Faraz Shafique

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.