NIH-funded research NIH-funded research

Performance-driven EEG-based brain-computer interface to help with brain conditions

Official title: Performance-Driven Adaptation to Maximise Efficiency of Electroencephalography-based Brain-Computer Interfaces

Funded at Duke University · NIH-11347340 · Data updated 2026-11-12

A Duke study aims to make noninvasive EEG brain-computer interfaces smarter and more reliable for people who could benefit from assistive communication and brain-activity monitoring.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startSeptember 14, 2026
Project endJune 30, 2029
Funding year2026
Award (this year)$1,552,943
NIH project number1RF1NS148614-01
Project IDNIH-11347340 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include individuals with neurological conditions affecting communication or motor function who could use EEG-based BCIs, including those at risk for Alzheimer’s disease dementia, Alzheimer's syndrome, or ALS/MND.

Less likely to help

Patients without access to EEG equipment or those with conditions that make BCI use impractical may see little direct benefit.

What this research studies

This project will develop real-time adaptive settings for EEG-based brain-computer interfaces, especially focusing on P300 BCIs, to cope with noisy and changing brain signals. It combines neuroscience, psychology, machine learning, and information theory to tune system parameters on the fly with low overhead and minimal user disruption. The goal is to improve accuracy and reliability so that users—particularly those with neurological conditions or communication challenges—can rely on BCIs for safer, easier interaction. The work will be conducted at Duke University under the lead of Dr. Boyla M Mansah.

Why it matters

Potential benefit: If successful, this approach could enable more dependable and user-friendly brain-computer interfaces for patients who need assistive communication or neuro-monitoring.

How similar studies have gone: Preliminary work in adaptive BCIs suggests potential gains, but real-time, patient-specific adaptation remains an area with opportunity for significant impact.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Mainsah, Boyla — Duke University
  • Study coordinator: Mainsah, Boyla

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.