NIH-funded research NIH-funded research

MXene EEG electrodes to improve brain monitoring

Official title: Validating MXene Electrodes for Next-Generation Electroencephalography

Funded at University of Pennsylvania · NIH-11605234 · Data updated 2026-11-12

Aims to validate a new, dry MXene-based EEG electrode system that could make brain monitoring simpler, more comfortable, and usable at home or in clinics.

More Electroencephalography research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startJune 1, 2021
Project endAugust 31, 2027
Funding year2026
Award (this year)$731,669
NIH project number2R56NS121219-06
Project IDNIH-11605234 on NIH RePORTER

Who could benefit from this research

Could help

Adults who need EEG monitoring or research participation related to brain activity, including routine or extended monitoring.

Less likely to help

Patients not requiring EEG monitoring or those with conditions outside cerebral monitoring needs may not directly benefit.

What this research studies

This project tests MXene-based dry EEG electrodes to replace traditional gel-based ones, with the goal of improving comfort and long-term signal stability. Researchers compare impedance, signal quality, MRI/TMS compatibility, and overall user experience against standard systems in various settings. The study builds on prior work showing dry MXene electrodes can perform as well or better than gelled electrodes. If successful, this approach could enable easier, more continuous brain monitoring for patients and for brain-computer interface applications.

Why it matters

Potential benefit: If successful, patients could experience more comfortable and reliable EEG monitoring at home or in clinics, with fewer skin irritations and less preparation time.

How similar studies have gone: Previous work demonstrated that MXene dry electrodes can match or exceed conventional gel-based EEG in impedance and signal quality.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Vitale, Flavia — University of Pennsylvania
  • Study coordinator: Vitale, Flavia

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.