Pain, Mood, and Thinking Problems in HIV- and AUD-risk Patients
Official title: Pain, Negative Affect, and Cognitive Dysfunction at the Intersection of HIV and AUD Risk
Funded at Lsu Health Sciences Center · NIH-11416382 · Data updated 2026-11-12
A long-running NIH grant explores how alcohol use, HIV, and negative feelings affect thinking and pain, with the goal of improving care for people living with HIV who struggle with alcohol-related problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Health Sciences Center NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | December 1, 1996 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $56,818 |
| NIH project number | 5P60AA009803-33 |
| Project ID | NIH-11416382 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with HIV who have alcohol use disorder and experience related cognitive or mood challenges.
✕Less likely to help
Individuals without HIV or AUD or without cognitive/mood symptoms related to these conditions may not directly benefit.
What this research studies
This grant brings together experts to study how alcohol use disorder and HIV interact to influence brain function, pain, and mood. The team uses human data and brain-behavior analyses to understand why cognitive and emotional problems occur in people with HIV who drink heavily. By linking pain, negative emotions, and cognitive function, the research aims to identify targets that could improve treatment adherence and quality of life. The work involves patients with HIV and AUD, and it seeks to translate findings into better clinical strategies.
Why it matters
Potential benefit: Findings could lead to better mental health support and pain management for people with HIV who have AUD, potentially improving cognitive health and ART adherence.
How similar studies have gone: Previous work shows that HIV-associated neurocognitive issues and AUD interact to worsen outcomes, supporting the relevance of this approach.
Where this research is happening
-
Lsu Health Sciences Center
New Orleans, United States Active
Researchers
- Principal investigator: Edwards, Scott — Lsu Health Sciences Center
- Study coordinator: Edwards, Scott
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.