Online lifestyle program to reduce obese frailty in men with prostate cancer on hormone therapy
Official title: Internet-Based Lifestyle Intervention to Eradicate Obese Frailty in Prostate Cancer Survivors (iLIVE)
Funded at Oregon Health & Science University · NIH-11323443 · Data updated 2026-11-12
A digital program combines diet and online exercise to help men with prostate cancer who are on hormone therapy lose excess weight and improve frailty.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | June 22, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $573,257 |
| NIH project number | 5R01CA275055-04 |
| Project ID | NIH-11323443 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are men with prostate cancer on androgen deprivation therapy who are experiencing obesity and frailty.
✕Less likely to help
Patients not on ADT or without obesity/frailty may not benefit from this specific program.
What this research studies
This project aims to help men with prostate cancer who are on androgen deprivation therapy by combining online dietary guidance with remotely supervised resistance training. The program is designed to be scalable and accessible, reaching many patients without requiring clinic visits. It focuses on reducing obesity-related frailty to improve independence and quality of life while potentially lowering health care costs.
Why it matters
Potential benefit: If successful, the program could help PCS on ADT stay more independent and healthier through easier weight management and stronger muscles.
How similar studies have gone: Prior online dietary and online resistance-training interventions have shown promise in reducing obesity and frailty in similar populations, supporting this combined approach.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Winters-Stone, Kerri M — Oregon Health & Science University
- Study coordinator: Winters-Stone, Kerri M
Related research
Other NIH-funded projects on the same topics.
-
Online program to help prostate cancer survivors manage obesity and frailty
This study is testing an online program that helps prostate cancer survivors who are dealing with weight gain and weakness from their treatment, by offering them healthy eating tips and guided exercise to boost their health and well-being.
-
Family-centered lifestyle program to help Black men with prostate cancer and their caregivers
A family-based program helps Black men with prostate cancer and their caregivers adopt healthier eating and more physical activity to improve overall well-being.
-
Long-term mental health after prostate cancer for survivors and their partners
This project looks at how prostate cancer and its treatment affect the long-term mental health of men who had prostate cancer and their partners.
-
Proactive Outreach and streamlined genetic testing for prostate cancer survivors
Aims to help prostate cancer survivors learn about and receive genetic testing so they and their families understand cancer risk and guide treatment.
-
Weight Loss, Bone Health, and Fracture Risk in Type 2 Diabetes
This project explores why people with type 2 diabetes who lose weight through an intensive program might have a higher chance of bone fractures.
-
Mental health outcomes in prostate cancer survivors and their partners
This study is looking at how surviving prostate cancer affects the mental health of men and their partners over time, to help find ways to support them better.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.