Obstructive sleep apnea and blood sugar control in adults with type 1 diabetes
Official title: Obstructive sleep apnea and glycemic dysregulation in adults with type 1 diabetes
Funded at University of Chicago · NIH-11412692 · Data updated 2026-11-12
This study tests whether treating sleep apnea improves blood sugar control in adults with type 1 diabetes who use insulin pumps and continuous glucose monitoring.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $675,024 |
| NIH project number | 5R01HL174685-03 |
| Project ID | NIH-11412692 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+) with type 1 diabetes and diagnosed obstructive sleep apnea who use an insulin pump and continuous glucose monitoring.
✕Less likely to help
Participants without obstructive sleep apnea or those not on CGM/insulin pump therapy may not benefit from this intervention.
What this research studies
If you have type 1 diabetes and sleep apnea, this study will compare what happens to your blood sugar and hormone responses when sleep apnea is untreated versus treated with CPAP over two 14-day periods. It uses a within-subject, cross-over design so participants experience both conditions in random order, with a 4-week washout between periods. Researchers will monitor sleep, hormones, lipids, and glucose using in-lab assessments and your CGM data to understand how sleep health affects glycemic control. The goal is to see if treating sleep apnea can reduce cardiovascular risk by improving glucose regulation in adults with type 1 diabetes.
Why it matters
Potential benefit: If successful, treating sleep apnea could improve blood sugar control and lower cardiovascular risk for adults with type 1 diabetes.
How similar studies have gone: Previous research supports a link between sleep apnea treatment and metabolic outcomes, but this study uses a rigorous cross-over design in type 1 diabetes.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Tasali, Esra — University of Chicago
- Study coordinator: Tasali, Esra
Related research
Other NIH-funded projects on the same topics.
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Sleep apnea and blood sugar control in adults with type 1 diabetes
This project looks at whether treating sleep apnea can improve blood sugar control for adults with type 1 diabetes who use insulin pumps and continuous glucose monitors.
-
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This study tests two treatment approaches to help adults with type 1 diabetes who often don’t realize their blood sugar is getting too low, using a mix of technology and education in two large groups.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.