Observing fertilization processes in mice
Official title: In vivo imaging of mammalian fertilization
Funded at Baylor College of Medicine · NIH-11022843 · Data updated 2026-11-12
This study is testing a new way to see how fertilization happens in the fallopian tubes of mice, which could help scientists understand the process better and improve treatments for infertility.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $674,095 |
| NIH project number | 1R01HD116768-01 |
| Project ID | NIH-11022843 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals experiencing difficulties conceiving or those interested in assisted reproductive technologies.
✕Less likely to help
Patients who are not seeking to conceive or who do not have reproductive health concerns may not receive direct benefits from this research.
What this research studies
This research aims to develop a new imaging technology that allows scientists to directly observe the fertilization process within the fallopian tubes of mice. By using this innovative approach, researchers hope to gain insights into the complex interactions between eggs, sperm, and the reproductive environment that are crucial for successful fertilization and early pregnancy. The study focuses on understanding these processes in vivo, which means observing them in their natural biological context rather than through extracted tissues or low-resolution images. This could lead to improved infertility treatments and advancements in assisted reproductive technologies.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of fertilization, potentially leading to better infertility treatments and assisted reproductive technologies.
How similar studies have gone: While the approach of in vivo imaging in reproductive biology is innovative, similar methodologies have shown promise in other areas of biological research, suggesting potential for success in this field as well.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Larina, Irina — Baylor College of Medicine
- Study coordinator: Larina, Irina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.