Novel digital therapeutic app to help adults with PTSD
Official title: Development and Evaluation of a Novel Digital Therapeutic for Adults with Post-Traumatic Stress Disorder
Funded at Oui Therapeutics, INC · NIH-11536935 · Data updated 2026-11-12
A new mobile app-based treatment for adults living with PTSD aims to provide an accessible, personalized therapy option.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oui Therapeutics, INC NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | June 5, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $966,804 |
| NIH project number | 4R44MH136888-03 |
| Project ID | NIH-11536935 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years or older with PTSD who own a smartphone and are willing to use a digital therapeutic.
✕Less likely to help
Individuals without PTSD, those without access to a compatible smartphone, or those who cannot engage with digital therapy may not benefit.
What this research studies
This project plans to create and test OTX-601, a mobile digital therapeutic for PTSD. In Phase I, researchers will build a user-friendly app, find the best dosing approach, and assess feasibility, acceptability, and usability, plus run a small randomized trial to gauge preliminary efficacy. In Phase II, they will conduct a larger randomized trial to evaluate how well the app works in real-world use. If successful, the approach could broaden access to PTSD care outside traditional clinics.
Why it matters
Potential benefit: If successful, the app could offer a scalable, convenient treatment option for PTSD that reaches more people who face barriers to conventional care.
How similar studies have gone: Past digital therapeutics for mental health have shown promise, but efficacy can vary across apps and conditions.
Where this research is happening
-
Oui Therapeutics, INC
New Haven, United States Active
Researchers
- Principal investigator: Simon, Patricia — Oui Therapeutics, INC
- Study coordinator: Simon, Patricia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.