Neural links between walking and thinking in Alzheimer's disease and related dementias
Official title: Neural Correlates of Cognitive-Motor Interactions in ADRD Gait
Funded at University of Florida · NIH-11394594 · Data updated 2026-11-12
This grant aims to understand how brain signals related to movement and thinking interact in aging and Alzheimer’s-related conditions to find early signs and interventions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 18, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $801,426 |
| NIH project number | 5R01AG089050-03 |
| Project ID | NIH-11394594 on NIH RePORTER |
Who could benefit from this research
✓Could help
Older adults at risk for or diagnosed with AD/ADRD who have gait changes and cognitive concerns may be eligible.
✕Less likely to help
Individuals without gait or cognitive impairment related to aging or AD/ADRD are less likely to benefit.
What this research studies
If funded, researchers at the University of Florida will study how brain systems that control balance, movement, and memory work together in older adults with AD/ADRD. They will use brain imaging and gait assessments to explore how vestibular and hippocampal areas influence walking and cognitive tasks. The goal is to identify neural patterns that could serve as early biomarkers and guide new, timely therapies. This work brings together experts in aging, neuroscience, and movement to tackle a pressing health challenge.
Why it matters
Potential benefit: If successful, this work could yield early warning signs based on gait and brain signals and point to new interventions to slow progression.
How similar studies have gone: Previous research shows links between gait, balance, and cognition in aging, with emerging brain-imaging evidence supporting neural associations.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Seidler, Rachael D — University of Florida
- Study coordinator: Seidler, Rachael D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.