NIH-funded research R15 grant

Improving How the Great Toe Works and Its Link to Walking and Balance in Older Adults

Official title: Improving the Assessment of Great Toe Function and its Association with Gait and Balance in Older Adults

Funded at California State University San Marcos · NIH-11444186 · Data updated 2026-11-12

Researchers are testing new ways to measure how the big toe functions and how that relates to walking balance in adults, with a focus on older individuals.

More Balance research and trials

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionCalifornia State University San Marcos
NIH-funded
Lab location1 site (San Marcos, United States)
Project startSeptember 15, 2026
Project endAugust 31, 2028
Funding year2026
Award (this year)$541,168
NIH project number1R15AG098615-01A1
Project IDNIH-11444186 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults 21 years and older, including both younger and older adults, with varying health and disease statuses.

Less likely to help

People not able to participate due to age or other health conditions unrelated to toe function may see no direct benefit.

What this research studies

This project aims to see how novel measurements of big toe function relate to gait variability and balance in both younger and older adults, using a new device and methods. The team plans to move beyond simple toe-grip tests to capture submaximal force control, joint-angle-specific force, and how quickly force can be generated. By comparing results across age groups and health statuses, the study seeks to clarify how toe function influences walking safety and fall risk. The research will develop practical, ecologically relevant ways to assess toe performance that could inform future clinical or at-home assessments.

Why it matters

Potential benefit: If successful, the project could lead to better screenings and interventions to prevent falls by focusing on toe function.

How similar studies have gone: Past work suggests a link between toe strength and balance, but this study aims to provide clearer, clinically useful measurements.

Where this research is happening

  • California State University San Marcos
    San Marcos, United States
    Active

Researchers

  • Principal investigator: Nessler, Jeff Andrew — California State University San Marcos
  • Study coordinator: Nessler, Jeff Andrew

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.