Native-led health research center to improve pain, substance use, and mental health
Official title: Absentee Shawnee Tribal Health System: HEAL Initiative: Native Collective Research Effort to Enhance Wellness (N CREW) Program- Addressing Overdose, Substance Use, Mental Health, and Pain (OT2)
Funded at Absentee Shawnee Tribe of Oklahoma · NIH-11539109 · Data updated 2026-11-12
A tribally owned clinical research center is being built to understand and improve chronic pain and related substance use and behavioral health issues in the Absentee Shawnee community.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Absentee Shawnee Tribe of Oklahoma NIH-funded |
| Lab location | 1 site (Shawnee, United States) |
| Project start | August 1, 2024 |
| Project end | March 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $198,005 |
| NIH project number | 3OT2DA061113-01S2 |
| Project ID | NIH-11539109 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals within the Absentee Shawnee community experiencing chronic pain, substance use, or behavioral health challenges who seek care at AST clinics.
✕Less likely to help
Non-community members or individuals without access to AST clinics may not directly benefit.
What this research studies
This project establishes the AST Clinical Research Center within the Absentee Shawnee Tribal Health System to study pain, substance use, and mental health from a Native-led perspective. It creates governance, a tribal research workforce, and a secure data infrastructure that respects Indigenous data sovereignty. A mixed-methods pilot will combine clinical data with community members’ experiences to identify gaps in care and guide improvements at AST clinics. The work aims to prepare the tribe to lead future intervention studies that align with community values and priorities.
Why it matters
Potential benefit: If successful, the project could lead to more culturally aligned care for chronic pain and related behavioral health issues in the Absentee Shawnee community.
How similar studies have gone: This approach combines tribal governance, Indigenous data sovereignty, and mixed-methods research, a relatively unique but increasingly supported model for tribal health improvement.
Where this research is happening
-
Absentee Shawnee Tribe of Oklahoma
Shawnee, United States Active
Researchers
- Principal investigator: Miller, Alicia L — Absentee Shawnee Tribe of Oklahoma
- Study coordinator: Miller, Alicia L
Related research
Other NIH-funded projects on the same topics.
-
Improving PrEP and mental health/substance-use reach for Hispanic men through community-driven implementation
A team at the University of Miami is collaborating with HIV organizations to describe and share real-world methods that help more Hispanic men access PrEP and mental health or substance-use care, with plans to spread successful approaches to other regions.
-
Bringing PrEP and mental health/substance-use services to Hispanic men through community partnerships
This project works with local HIV organizations to spread practical ways to improve access to PrEP and mental health/substance-use care for Hispanic men.
-
Disrupting social risk factors to help parents in rural areas stay healthy
A community program is being tested to help parents in rural Oregon avoid substance use problems and improve mental health by addressing social risks like employment and local supports.
-
How racism shapes teens' substance use, mental health, and contact with the legal system into young adulthood
Researchers will re-contact teens who had juvenile legal involvement and their caregivers to track how experiences of racism relate to substance use, mental health, and later legal contact.
-
Reducing social hardships to help rural parents with substance use and mental health
This program offers the multi-part Just Care for Families support to rural parents to reduce problems like unemployment and housing stress so they can avoid opioid use and feel better mentally.
-
CHARTER Plus: improving brain and mental health for people with HIV and substance use
This project builds a long-term resource of brain tests, mental-health measures, and stored samples to help adults with and without HIV better understand and protect their brain health across life.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.