NIH-funded research R01 grant

How racism shapes teens' substance use, mental health, and contact with the legal system into young adulthood

Official title: The Impact of Racism on Trajectories of Substance Use, Mental Health and Legal System Contact from Adolescence to Young Adulthood

Funded at University of California, San Francisco · NIH-11381703 · Data updated 2026-11-12

Researchers will re-contact teens who had juvenile legal involvement and their caregivers to track how experiences of racism relate to substance use, mental health, and later legal contact.

More Mental Health research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startMay 15, 2022
Project endFebruary 28, 2027
Funding year2026
Award (this year)$715,271
NIH project number5R01DA056265-05
Project IDNIH-11381703 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents and young adults who had first contact with the juvenile legal system as teens and their involved caregivers, especially ethnoracially minoritized families previously enrolled in Project EPICC.

Less likely to help

People without prior juvenile legal system involvement or those not part of the original Project EPICC cohort are not the focus and are unlikely to be directly included or benefit immediately from participation.

What this research studies

This project follows up with 300 youth-caregiver pairs from Project EPICC and builds on existing longitudinal data from 401 youth to extend tracking into young adulthood. Participants will complete one annual follow-up assessment and life-course interviews about experiences of racism, substance use, mental health, and interactions with the legal system. New data will be linked to earlier measures of individual, family, and community risk and protective factors to map developmental trajectories. Analyses focus on structural, cultural, and individual racism and how these forces contribute to health and legal inequities for ethnoracially minoritized youth.

Why it matters

Potential benefit: If successful, findings could inform policies and programs to reduce racial disparities and improve supports for justice-involved youth and their families.

How similar studies have gone: Previous longitudinal work links discrimination to worse mental health and substance use, but extended follow-up of justice-involved, ethnoracial minoritized youth is relatively novel.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Tolou-Shams, Marina — University of California, San Francisco
  • Study coordinator: Tolou-Shams, Marina

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.