NIH-funded research R01 grant

Motivation Matters! a smartphone support tool to boost HIV medicines adherence in HIV+ sex workers

Official title: Hybrid Type-1 Effectiveness-Implementation Trial of Motivation Matters! A Theory-Based mHealth Intervention to Support Early Antiretroviral Adherence in HIV+ African Women Who Engage in Sex Work

Funded at University of Washington · NIH-11416458 · Data updated 2026-11-12

A smartphone-based program helps HIV+ women who sex-work with adherence to antiretroviral therapy, aiming to keep their HIV under control.

More Motivation research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 9, 2024
Project endJune 30, 2028
Funding year2026
Award (this year)$660,723
NIH project number5R01MH132536-03
Project IDNIH-11416458 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adult women living with HIV who engage in sex work and face adherence challenges.

Less likely to help

Individuals not using ART or not experiencing adherence difficulties may find limited benefit.

What this research studies

This project tests an interactive mobile health tool called Motivation Matters! designed with input from women who sex-work to support daily ART adherence. It combines an evidence-based theory with user-friendly prompts, reminders, and motivational content to help women maintain an undetectable viral load. The study uses a practical, real-world approach to fit into participants’ routines and evaluates both how well the app works and how feasible it is to implement in real clinics. Participants will be adult women who are living with HIV and engage in sex work, with outcomes focused on adherence and health results.

Why it matters

Potential benefit: If successful, the program could help more women stay adherent to HIV treatment, improving health and reducing transmission.

How similar studies have gone: Some prior mHealth approaches showed feasibility; this study builds on that with a theory-based, culture-informed design.

Where this research is happening

  • University of Washington
    Seattle, United States
    Active

Researchers

  • Principal investigator: Mcclelland, Raymond Scott — University of Washington
  • Study coordinator: Mcclelland, Raymond Scott

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.