Molecular and Cellular Phenotyping Core for metabolism research
Official title: Molecular and Cellular Phenotyping Core
Funded at Oklahoma Medical Research Foundation · NIH-11336056 · Data updated 2026-11-12
A new core service is being added to help researchers study which genes and proteins change in tissues and what those changes mean, using advanced imaging and tissue techniques.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | February 5, 2021 |
| Project end | March 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $323,950 |
| NIH project number | 2P20GM139763-06 |
| Project ID | NIH-11336056 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are researchers studying metabolism-related tissues who need advanced phenotyping services and training.
✕Less likely to help
Patients not involved in this research or trials would not directly benefit from participating.
What this research studies
This grant funds a center that offers specialized phenotyping services to identify genes and proteins that differ in tissues of interest and to explore their functional effects. Researchers will access expertise, training, and equipment to perform spatial transcriptomics, tissue processing, and imaging. The core includes advanced instruments like Vizgen MERSCOPE, a Nikon AXR microscope, and a Scanning Electron Microscope, plus protocols for high-detail vascular and tissue analyses. The goal is to provide centralized access so investigators can understand molecular changes in metabolism-related tissues.
Why it matters
Potential benefit: If successful, patients could benefit from accelerated insight into how metabolic changes affect tissues, potentially guiding diagnostics and therapies.
How similar studies have gone: Previous centers with similar phenotyping capabilities have advanced our understanding of tissue biology and metabolism, with successful translational insights.
Where this research is happening
-
Oklahoma Medical Research Foundation
Oklahoma City, United States Active
Researchers
- Principal investigator: Srinivasan, Rajanarayanan S — Oklahoma Medical Research Foundation
- Study coordinator: Srinivasan, Rajanarayanan S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.