Tissue research hub for autoimmune diseases to speed up new treatments
Official title: Accelerating Medicines Partnership-Autoimmune and Immunologic Disease Tissue Research Core
Funded at Oklahoma Medical Research Foundation · NIH-11590648 · Data updated 2026-11-12
A national program is building a centralized tissue core to study autoimmune diseases like lupus, rheumatoid arthritis, Sjögren’s, and psoriatic conditions using advanced single-cell and spatial analysis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | March 23, 2022 |
| Project end | December 31, 2026 |
| Funding year | 2026 |
| Award (this year) | $2,873,650 |
| NIH project number | 3UC2AR081032-05S1 |
| Project ID | NIH-11590648 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with lupus, rheumatoid arthritis, Sjögren’s syndrome, or psoriatic spectrum diseases who provide tissue samples or participate in related data collection.
✕Less likely to help
Direct participant benefits are not guaranteed; some individuals may contribute samples without immediate personal health benefits.
What this research studies
This project creates a centralized tissue research core to standardize sample collection, processing, and advanced molecular analyses across four autoimmune diseases. It will provide manuals, logistics, quality control, and tissue imaging to ensure high-quality, comparable data from patients. By doing so, it aims to accelerate discovery of meaningful cellular interactions and biomarkers that could guide new therapies for autoimmune conditions.
Why it matters
Potential benefit: If successful, patients with autoimmune diseases could benefit from faster development of targeted therapies and better biomarker-driven treatment decisions.
How similar studies have gone: Previous AMP efforts showed that integrating tissue data can reveal new targets; this program expands those methods to additional diseases and tissue types.
Where this research is happening
-
Oklahoma Medical Research Foundation
Oklahoma City, United States Active
Researchers
- Principal investigator: Guthridge, Joel Marvin — Oklahoma Medical Research Foundation
- Study coordinator: Guthridge, Joel Marvin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.