Mindfulness and optimism program for pregnant people

Mindfulness, Optimism and Resilience for Perinatal Health and Empowerment (MORPHE) Trial

NIH-funded research Miriam Hospital · NIH-11178502

This offers a mindfulness phone app for pregnant people with low optimism to help reduce traumatic birth experiences and postpartum stress.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMiriam Hospital NIH-funded
Lab location1 site (Providence, United States)
Project IDNIH-11178502 on NIH RePORTER

What this research studies

If I join, I would be randomly assigned to use a perinatal mindfulness app called Expectful or to receive usual prenatal care, with about 100 pregnant people taking part. The study focuses on people who report low dispositional optimism and follows them through birth and the postpartum period to track traumatic birth experiences, p-PTSD symptoms, depression, and anxiety. Researchers will check whether the app is easy to use and acceptable, whether it increases optimism and other resilience skills, and will gather participants' perspectives on how optimism shapes their pregnancy. Results will help the team plan a larger trial to bring this digital support to more pregnant people.

Who could benefit from this research

Good fit: Pregnant people who report low optimism, are within the study's recruitment area, and are willing to use a smartphone app are the ideal candidates.

Not a fit: People who are not pregnant, already have high optimism, lack a compatible smartphone, or require intensive psychiatric care are unlikely to benefit from this app-based trial.

Why it matters

Potential benefit: If successful, this could lower rates of traumatic birth experiences and postpartum PTSD and anxiety by boosting optimism through an accessible app.

How similar studies have performed: Mindfulness programs have reduced stress and improved well-being in other groups, but using a perinatal mindfulness app specifically to raise optimism and prevent p-PTSD is relatively new.

Where this research is happening

Providence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.