NIH-funded research R01 grant

Metacognitive Strategy Help for Parkinson’s-Related Thinking Difficulties

Official title: Efficacy and Mechanisms of a Metacognitive Strategy Intervention for Parkinson disease-related Cognitive Decline

Funded at Washington University · NIH-11399024 · Data updated 2026-11-12

Aimed at people with Parkinson’s disease who have thinking and memory challenges, this project tests a practical, everyday strategy approach to help with daily tasks and improve quality of life.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startSeptember 1, 2025
Project endAugust 31, 2030
Funding year2026
Award (this year)$763,015
NIH project number5R01AG094871-02
Project IDNIH-11399024 on NIH RePORTER

Who could benefit from this research

Could help

Adults with Parkinson’s disease who experience cognitive decline and related daily-function difficulties.

Less likely to help

People without Parkinson’s-related cognitive issues or those unable to participate in behavioral training may not benefit.

What this research studies

If you have Parkinson’s and experience cognitive difficulties, this study tests a strategy-based program called Multicontext to help you use practical tricks in daily activities. The researchers will guide participants through training that teaches generalizable strategies to cope with thinking and memory problems, with emphasis on applying them to real-life tasks. The study will compare outcomes to see if this approach reduces disability and helps people stay engaged in work, home duties, and social roles. Participation may involve cognitive training sessions and assessments of daily functioning over time. The aim is to translate cognitive support into meaningful improvements in day-to-day life for people living with PD.

Why it matters

Potential benefit: If successful, the program could help people with PD think more clearly and perform daily activities more independently.

How similar studies have gone: Strategy-based cognitive rehabilitation is standard in other brain injuries but is being tested here for PD with promising potential.

Where this research is happening

  • Washington University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Foster, Erin — Washington University
  • Study coordinator: Foster, Erin

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.