Mechanomyography-based diagnostic tool for nerve function during pain procedures
Official title: Mechanomyography-based system for quantitative nerve assessment during standard pain management procedures
Funded at Neuralytix, LLC · NIH-11403158 · Data updated 2026-11-12
A new MMG-based diagnostic system aims to give objective, quantitative measurements of nerve function during routine preoperative pain management procedures.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Neuralytix, LLC NIH-funded |
| Lab location | 1 site (Fruita, UNITED STATES) |
| Project start | August 7, 2026 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $353,059 |
| NIH project number | 1R43GM162022-01A1 |
| Project ID | NIH-11403158 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults with suspected nerve compression considering preoperative pain management and potential decompression surgery.
✕Less likely to help
Individuals without nerve compression or those not undergoing preoperative pain management may not benefit.
What this research studies
This project develops a mechanomyography (MMG) diagnostic system to quantify nerve compression during preoperative pain blocks. Researchers will test measurement consistency and reliability across different users and body regions using a pig model before moving toward human use. The goal is to transform nerve blocks from qualitative assessments to quantitative diagnostics, helping doctors choose the best decompression options. The approach builds on validated MMG technology that detects nerve responses and aims to standardize measurements across clinical settings.
Why it matters
Potential benefit: If successful, patients may receive more accurate nerve status information, potentially leading to better-targeted decompression decisions and improved pain relief.
How similar studies have gone: Prior MMG-based methods have shown promise in detecting nerve responses, but this project extends validation toward a quantitative diagnostic in a clinical workflow.
Where this research is happening
-
Neuralytix, LLC
Fruita, United States Active
Researchers
- Principal investigator: Wybo, Chris — Neuralytix, LLC
- Study coordinator: Wybo, Chris
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.