NIH-funded research NIH-funded research

Building Indigenous Research Infrastructure for Substance Misuse and Pain Management

Official title: Building iCRISP: Indigenous Community-Informed Research Infrastructure to address Substance Misuse and Pain Management

Funded at Lumbee Land Development, INC. · NIH-11553670 · Data updated 2026-11-12

A planned two-year effort helps the Lumbee Tribe build a community-led research infrastructure to better understand and address substance misuse and pain in their community.

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Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLumbee Land Development, INC.
NIH-funded
Lab location1 site (Pembroke, United States)
Project startAugust 15, 2024
Project endJuly 31, 2027
Funding year2026
Award (this year)$634,721
NIH project number3OT2DA061140-01S2
Project IDNIH-11553670 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are Lumbee community members and partners who will engage in planning and governance of the research infrastructure and potential future studies.

Less likely to help

Individuals not involved in this planning phase or who do not participate in community governance may not directly benefit from the infrastructure development.

What this research studies

This project centers the Lumbee Tribe in North Carolina to create a trusted, community-informed research framework. It brings together the Lumbee-led organization CORE, state health partners, and multiple research groups to plan and coordinate how data, people, and resources can be used responsibly. The goal is to develop a structured approach to studying health outcomes, with emphasis on substance misuse and pain, while aligning with tribal priorities and values. The work will lay the groundwork for future studies that could inform prevention, care, and policy in the Lumbee community.

Why it matters

Potential benefit: If successful, the project could lead to better health outcomes through culturally informed research and more effective, community-guided strategies for substance misuse and pain management.

How similar studies have gone: Community-based, tribal-led research infrastructures have shown promise in guiding culturally appropriate health interventions.

Where this research is happening

  • Lumbee Land Development, INC.
    Pembroke, United States
    Active

Researchers

  • Principal investigator: Hunt, Celeste — Lumbee Land Development, INC.
  • Study coordinator: Hunt, Celeste

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.