Massed PTSD Treatment in a Community Substance Use Program
Official title: Hybrid Effectiveness-Implementation Trial of Massed PTSD Treatment in a Community Substance Use Program
Funded at Rutgers, the State Univ of N.j. · NIH-11361601 · Data updated 2026-11-12
A community program will test a faster, intensified PTSD treatment delivered alongside substance use care to help people with both conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | September 3, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $664,780 |
| NIH project number | 5R01MH132720-03 |
| Project ID | NIH-11361601 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with co-occurring PTSD and substance use disorder enrolled in intensive outpatient treatment.
✕Less likely to help
Patients without PTSD or who cannot participate in exposure-based therapy may not benefit.
What this research studies
This project tests delivering Prolonged Exposure therapy in a massed format (multiple sessions per week) within an intensive outpatient substance use program. It aims to see whether moving to a quicker, concentrated treatment improves attendance and PTSD/SUD outcomes. The study builds on evidence that using PE for PTSD is effective and safe when paired with substance use treatment, and it explores real-world implementation in a community setting. Patients enrolled in the IOP SUD program who have PTSD would be offered the massed PE format alongside standard care, with comparable follow-up to assess long-term effects.
Why it matters
Potential benefit: If successful, patients could experience better PTSD symptoms and substance-use outcomes through a more accessible treatment approach.
How similar studies have gone: Prior research supports massed PE as feasible and may reduce dropout compared to weekly sessions, with promise for PTSD/SUD populations.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Hien, Denise Aimee — Rutgers, the State Univ of N.j.
- Study coordinator: Hien, Denise Aimee
Related research
Other NIH-funded projects on the same topics.
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Written Exposure Therapy for Veterans with PTSD and Substance Use Disorder (brief trauma treatment)
A brief trauma-focused therapy called Written Exposure Therapy is being studied to help veterans who have both PTSD and substance use disorders.
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Web-based training to treat PTSD and substance use together in Veterans
A web-based training resource helps VA clinicians learn how to provide integrated treatment for Veterans with both PTSD and substance use disorders.
-
Genetics of PTSD and Substance Use in Diverse Populations
This grant investigates how genes influence PTSD and substance use disorders in diverse groups to improve prevention and treatment.
-
Using Written Exposure Therapy to help Veterans with PTSD and Substance Use Disorders
This study is looking at how helpful Written Exposure Therapy can be for Veterans dealing with both PTSD and substance use issues, especially for those in rural areas who might not have easy access to care, to see if it can make their treatment better and improve their quality of life.
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Online training for clinicians to deliver COPE, a combined PTSD and substance-use therapy
This project offers web training to teach VA clinicians how to deliver COPE, a combined Prolonged Exposure therapy for Veterans with PTSD and substance use problems.
-
Improving PTSD Treatment for People in Substance Use Care
This research aims to make a proven PTSD treatment more accessible and effective for individuals also receiving care for substance use.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.