NIH-funded research R01 grant

Massed PTSD Treatment in a Community Substance Use Program

Official title: Hybrid Effectiveness-Implementation Trial of Massed PTSD Treatment in a Community Substance Use Program

Funded at Rutgers, the State Univ of N.j. · NIH-11361601 · Data updated 2026-11-12

A community program will test a faster, intensified PTSD treatment delivered alongside substance use care to help people with both conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers, the State Univ of N.j.
NIH-funded
Lab location1 site (Piscataway, United States)
Project startSeptember 3, 2024
Project endJune 30, 2029
Funding year2026
Award (this year)$664,780
NIH project number5R01MH132720-03
Project IDNIH-11361601 on NIH RePORTER

Who could benefit from this research

Could help

Adults with co-occurring PTSD and substance use disorder enrolled in intensive outpatient treatment.

Less likely to help

Patients without PTSD or who cannot participate in exposure-based therapy may not benefit.

What this research studies

This project tests delivering Prolonged Exposure therapy in a massed format (multiple sessions per week) within an intensive outpatient substance use program. It aims to see whether moving to a quicker, concentrated treatment improves attendance and PTSD/SUD outcomes. The study builds on evidence that using PE for PTSD is effective and safe when paired with substance use treatment, and it explores real-world implementation in a community setting. Patients enrolled in the IOP SUD program who have PTSD would be offered the massed PE format alongside standard care, with comparable follow-up to assess long-term effects.

Why it matters

Potential benefit: If successful, patients could experience better PTSD symptoms and substance-use outcomes through a more accessible treatment approach.

How similar studies have gone: Prior research supports massed PE as feasible and may reduce dropout compared to weekly sessions, with promise for PTSD/SUD populations.

Where this research is happening

  • Rutgers, the State Univ of N.j.
    Piscataway, United States
    Active

Researchers

  • Principal investigator: Hien, Denise Aimee — Rutgers, the State Univ of N.j.
  • Study coordinator: Hien, Denise Aimee

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.