Mapping the changes in human lymphomas over time and space
Official title: Center for Human Lymphoma Spatiotemporal Atlas (HuLymSTA)
Funded at Yale University · NIH-10994872 · Data updated 2026-11-12
This study is looking at how non-Hodgkin lymphomas, especially B-cell and T-cell types, change and grow over time, so we can better understand these cancers and find new ways to help patients through improved treatments and tests.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,018,682 |
| NIH project number | 1U01CA294514-01 |
| Project ID | NIH-10994872 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with non-Hodgkin lymphomas, particularly those with follicular lymphoma or angioimmunoblastic T-cell lymphoma.
✕Less likely to help
Patients with other types of cancers or those without a diagnosis of lymphoma may not receive any benefit from this research.
What this research studies
This research investigates the complex biology of non-Hodgkin lymphomas, particularly focusing on B-cell and T-cell types, to understand how these cancers evolve and transform. By creating a detailed atlas of lymphomas, the study aims to identify the spatial and temporal changes in tumor architecture and the surrounding microenvironment. Patients may benefit from insights gained into the mechanisms of lymphoma progression, which could lead to the development of new biomarkers and therapies. The research employs advanced imaging and biological techniques to analyze tumor samples and their interactions with surrounding tissues.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for patients with aggressive lymphomas.
How similar studies have gone: Previous research has shown promise in understanding lymphoma biology through similar approaches, but this specific atlas methodology is relatively novel.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Fan, Rong — Yale University
- Study coordinator: Fan, Rong
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.