Radiation Therapy Innovation to Improve Lymphoma Trials and Carbon Ion Research Path
Official title: Radiation Oncology Integration and innovation: Enhancing Lymphoma Trial Design and Establishing a Particle Therapy Research Pathway
Funded at Mayo Clinic Jacksonville · NIH-11448035 · Data updated 2026-11-12
A Mayo Clinic-led effort to better design and run lymphoma trials by integrating advanced radiation therapy and exploring carbon ion radiotherapy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $163,320 |
| NIH project number | 1R50CA305246-01A1 |
| Project ID | NIH-11448035 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with hematologic malignancies who are eligible for NCTN lymphoma trials and receive radiation therapy at participating centers.
✕Less likely to help
Patients not enrolled in NCTN lymphoma trials or those not receiving radiation therapy may not directly benefit.
What this research studies
This grant supports national leadership to weave radiation therapy into large cooperative cancer trials and to raise the quality and consistency of RT in those trials. It includes building a robust RT quality assurance framework, mentoring new investigators, and expanding trial enrollment at Mayo Clinic in Jacksonville. A key goal is to develop a framework for incorporating carbon ion radiotherapy into NCTN research, with collaborative efforts across major cancer groups. The project aims to harmonize RT practices, dose constraints, and credentialing to help patients with hematologic cancers participate in cutting-edge trials.
Why it matters
Potential benefit: Patients with hematologic cancers could access better-designed trials and potentially more effective, precisely targeted radiation therapies.
How similar studies have gone: Previous collaborations have established guidelines and harmonized practices across groups, suggesting potential for meaningful improvements with this approach.
Where this research is happening
-
Mayo Clinic Jacksonville
Jacksonville, United States Active
Researchers
- Principal investigator: Hoppe, Bradford S — Mayo Clinic Jacksonville
- Study coordinator: Hoppe, Bradford S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.