Mapping how cells organize their internal structures
Official title: Quantitative super-resolution imaging to map the multi-scale functional organization of cells
Funded at University of Pennsylvania · NIH-10762873 · Data updated 2026-11-12
This study is looking at how cells arrange their parts, like tiny organs and proteins, and how this organization affects their health, which could help us find new ways to treat diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 7, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $426,363 |
| NIH project number | 1R35GM152111-01 |
| Project ID | NIH-10762873 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with diseases linked to cellular dysfunction or abnormalities in cellular organization.
✕Less likely to help
Patients with conditions unrelated to cellular organization or those not experiencing cellular dysfunction may not benefit from this research.
What this research studies
This research investigates the mechanisms that control how cells organize their internal components, such as organelles and proteins, at various scales. By using advanced imaging techniques, the study aims to understand how these organizational patterns affect cell function and how disruptions in this organization can lead to diseases. Patients may benefit from insights gained about the relationship between cellular organization and health, potentially leading to new therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases caused by cellular organization disruptions.
How similar studies have gone: Other research has shown promising results in understanding cellular organization and its implications for disease, indicating that this approach has potential for success.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Lakadamyali, Melike — University of Pennsylvania
- Study coordinator: Lakadamyali, Melike
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.