Mapping aging cells in human tissues
The KAPP-Sen Tissue Mapping Center Collaborative
This study is looking at how aging changes certain cells in different parts of the body, like the kidneys and fat, and it needs tissue samples from patients to help researchers learn more about these aging cells and how they might affect health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Sch of Med/dnt NIH-funded |
| Lab location | 1 site (Farmington, United States) |
| Project ID | NIH-10907726 on NIH RePORTER |
What this research studies
This research focuses on understanding how aging affects cells in various human tissues, including the kidney, adipose tissue, pancreas, and placenta. By collaborating with six leading institutions, the project aims to identify and characterize senescent cells, which are cells that have stopped dividing and contribute to aging and chronic diseases. Patients may provide tissue samples, which will help researchers map the distribution and biological differences of these cells across healthy tissues. This collaborative effort is part of a larger initiative to improve our understanding of cellular aging and its implications for health.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals who are undergoing procedures that allow for tissue sampling, particularly those related to the kidney, adipose tissue, pancreas, or placenta.
Not a fit: Patients with acute or severe health conditions that prevent them from providing tissue samples may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into aging and chronic diseases, potentially informing future treatments and interventions.
How similar studies have performed: Previous research in cellular senescence has shown promising results, indicating that understanding these processes can lead to significant advancements in aging-related health issues.
Where this research is happening
Farmington, United States
- University of Connecticut Sch of Med/dnt — Farmington, United States (Active)
Researchers
- Principal investigator: Kuchel, George a — University of Connecticut Sch of Med/dnt
- Study coordinator: Kuchel, George a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.