NIH-funded research R01 grant

Look AHEAD Aging Extension for older adults with type 2 diabetes

Official title: Look AHEAD Aging Extension

Funded at Wake Forest University Health Sciences · NIH-11446617 · Data updated 2026-11-12

A study of people with type 2 diabetes and overweight or obesity to find ways to promote healthier aging and better quality of life in later years.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences
NIH-funded
Lab location1 site (Winston-Salem, United States)
Project startSeptember 15, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$958,745
NIH project number1R01AG097598-01A1
Project IDNIH-11446617 on NIH RePORTER

Who could benefit from this research

Could help

Older adults (mid- to late-life) with type 2 diabetes who are overweight or have obesity and have prior Look AHEAD study involvement or data linkage opportunities.

Less likely to help

Patients not fitting the age range, without type 2 diabetes or with normal weight, or who are not linked to Look AHEAD data.

What this research studies

This project will look at long-term data from the Look AHEAD group to identify lifestyle, physical health, mental health, and clinical care factors that help people with type 2 diabetes age more healthily. Researchers will analyze how modifiable behaviors and care strategies relate to fewer chronic diseases, lower healthcare use and costs, and preserved function and well-being in mid- to late life. The goal is to uncover actionable factors that could guide personalized care plans for aging patients with diabetes.

Why it matters

Potential benefit: If successful, findings could inform personalized lifestyle and care interventions to improve healthspan and quality of life for older adults with type 2 diabetes.

How similar studies have gone: The Look AHEAD cohort has long-term data; the study builds on established relationships to aging outcomes in diabetes.

Where this research is happening

  • Wake Forest University Health Sciences
    Winston-Salem, United States
    Active

Researchers

  • Principal investigator: Houston, Denise Kathryn — Wake Forest University Health Sciences
  • Study coordinator: Houston, Denise Kathryn

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.