Long-term study of a nationwide group of people with interstitial cystitis
Official title: RFA-DP-24-031: Longitudinal Follow-up of a Nationwide Multiethnic Cohort of Veterans and Non-Veterans with Interstitial Cystitis
Funded at University of California, San Diego · NIH-11422054 · Data updated 2026-11-12
A nationwide group of people with interstitial cystitis and similar cases will be followed over several years to understand how the condition progresses and how treatments work in real life.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 30, 2024 |
| Project end | September 29, 2029 |
| Funding year | 2026 |
| Award (this year) | $830,000 |
| NIH project number | 5U01DP006830-03 |
| Project ID | NIH-11422054 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with interstitial cystitis/bladder pain syndrome who have been diagnosed or confirmed through chart review will be considered.
✕Less likely to help
Patients without a confirmed IC diagnosis or not enrolled in the cohort may not benefit directly from the study.
What this research studies
This project follows a large, diverse group of veterans and non-veterans with interstitial cystitis over time to map how the disease evolves, what treatments are used, and how other conditions like depression or PTSD may relate to outcomes. Researchers will use existing health records and periodic checks to track symptoms, diagnoses, and care patterns. The goal is to identify markers that predict progression, treatment response, and disparities in care across race, gender, geography, and socioeconomic status.
Why it matters
Potential benefit: People with interstitial cystitis could benefit from better ways to predict who will worsen, who responds to treatment, and how to receive more consistent care.
How similar studies have gone: Previous work established national prevalence and identified key questions; this study builds on that foundation to follow patients over time.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Anger, Jennifer Tash — University of California, San Diego
- Study coordinator: Anger, Jennifer Tash
Related research
Other NIH-funded projects on the same topics.
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Understanding spinal cord cell roles in bladder pain and function
A study to map which spinal cord cells process bladder sensations and how they contribute to bladder pain and voiding problems in IC/BPS.
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How bladder support cells control the lining and bladder pain
Researchers are exploring whether special support cells in the bladder control nerve overgrowth and damage to the bladder lining in people with interstitial cystitis/bladder pain syndrome (IC/BPS).
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Spinal Cord Signals and bladder pain in IC/BPS
A new NIH grant looks at how specific spinal cord cells control bladder function and bladder pain in people with IC/BPS, aiming to uncover targets for future therapies.
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Personalized treatments for bladder pain (interstitial cystitis)
A treatment approach aiming at the underlying causes of bladder pain for people with interstitial cystitis/bladder pain syndrome.
-
Spinal cord cell types that drive bladder pain in interstitial cystitis (IC/BPS)
Researchers will use precise lab tools to find which spinal cord cells cause bladder pain and troublesome urination in people with interstitial cystitis/bladder pain syndrome (IC/BPS).
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National long-term follow-up of people with interstitial cystitis (bladder pain)
Following people with interstitial cystitis across the U.S. to learn how symptoms, treatments, and related health conditions change over time.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.