National long-term follow-up of people with interstitial cystitis (bladder pain)

RFA-DP-24-031: Longitudinal Follow-up of a Nationwide Multiethnic Cohort of Veterans and Non-Veterans with Interstitial Cystitis

NIH-funded research University of California, San Diego · NIH-11163191

Following people with interstitial cystitis across the U.S. to learn how symptoms, treatments, and related health conditions change over time.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11163191 on NIH RePORTER

What this research studies

If you join, researchers will follow a nationwide, multiethnic group of people with interstitial cystitis using medical record review, regular surveys, and clinical data collected over several years. They will compare veterans and non-veterans and look for links between bladder pain, treatments, mental health conditions like depression or PTSD, and social factors such as race, gender, and where you live. The team will also explore whether urine tests can help predict who will get worse or improve. Data from the Veterans Affairs system and other participating health systems will be combined to track typical care patterns and outcomes.

Who could benefit from this research

Good fit: Adults with a documented diagnosis of interstitial cystitis/bladder pain syndrome, including veterans and non-veterans from diverse racial and geographic backgrounds, are the ideal candidates.

Not a fit: People without IC or whose bladder pain is clearly caused by other conditions such as active urinary infection, stones, or bladder cancer are unlikely to benefit directly.

Why it matters

Potential benefit: This work could reveal patterns that lead to earlier diagnosis, better-targeted treatments, and improved monitoring for people with IC.

How similar studies have performed: Previous CDC-funded work created a national IC cohort and estimated prevalence, but applying urine biomarkers and long-term follow-up to predict disease course is relatively new and not yet proven.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.