LARKSPUR-mHealth: a remote positive-emotion program for fibromyalgia
Official title: LARKSPUR-mHealth: A Randomized Controlled Trial of a Remotely Delivered Positive Affect Intervention for Fibromyalgia
Funded at Cornell University · NIH-11443107 · Data updated 2026-11-12
A nationwide, fully online program tests whether brief daily skills to boost positive emotions can ease pain and improve daily life for adults with fibromyalgia.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project start | August 15, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $853,712 |
| NIH project number | 1R01AT013458-01A1 |
| Project ID | NIH-11443107 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21+ with fibromyalgia who can participate in a fully online program and complete remote assessments.
✕Less likely to help
Some participants may not experience meaningful pain relief or functional improvement.
What this research studies
This study recruits 400 adults with fibromyalgia to participate in a 6-week online program called LARKSPUR that teaches gratitude, savoring, reframing, and kindness to help reduce pain impact. Participants are randomly assigned to the LARKSPUR program or an active control that mirrors time and attention with daily emotion reporting. The trial uses remote assessments to measure pain interference, pain intensity, and analgesic use, with follow-ups up to 12 months. Data are securely collected and overseen to ensure diagnostic accuracy and participant safety while striving for diverse enrollment.
Why it matters
Potential benefit: If successful, participants may experience less pain interference and better function, potentially reducing the burden of fibromyalgia.
How similar studies have gone: Prior work suggests behavioral strategies can modestly reduce pain impact, but large remote trials for fibromyalgia are still needed.
Where this research is happening
-
Cornell University
Ithaca, United States Active
Researchers
- Principal investigator: Ong, Anthony D — Cornell University
- Study coordinator: Ong, Anthony D
Related research
Other NIH-funded projects on the same topics.
-
Cognitive behavioral therapy and trazodone for insomnia phenotypes with high blood pressure
A clinical study tests how CBT-I and the sleep drug trazodone work for adults with insomnia and high blood pressure, focusing on a specific sleep duration pattern.
-
Shorter antifungal treatment for kids with candidemia
A multi-center pediatric trial tests whether a shorter, 7 extra days of antifungal therapy after an initial 7 days is just as good as the standard 14-day approach for kids with candidemia who are improving on echinocandin therapy.
-
Short Course vs Standard Course Antifungal Therapy for Pediatric Candidemia
This study tests whether a shorter 7-day total antifungal treatment after an initial 7 days of echinocandin therapy is as effective as the usual 14-day course for children with candidemia.
-
Shorter antifungal treatment for kids with candidemia
A multi-center study tests whether kids with candidemia can finish treatment earlier after an initial week of antifungal therapy than the standard two weeks total.
-
Shorter antifungal treatment for kids with candidemia
This study tests whether children with candidemia can finish treatment after 7 days of an echinocandin if they are improving, instead of completing a full 14 days.
-
Shorter antifungal course for kids with candidemia
A multi-center study tests whether 7 extra days of antifungal therapy after an initial week of treatment can be shortened safely for children with candidemia.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.