Investigating how specific brain signaling affects learning and memory.
Official title: In Vivo Analyses of Kinase Signaling in Learning/Memory Circuitry
Funded at Vanderbilt University · NIH-10993637 · Data updated 2026-11-12
This study is looking at how certain signals in the brain affect learning and memory, and it aims to help people with memory problems or epilepsy by finding new ways to improve their conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $377,518 |
| NIH project number | 5R01NS131557-02 |
| Project ID | NIH-10993637 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with learning and memory impairments or epilepsy.
✕Less likely to help
Patients with conditions unrelated to learning, memory, or neurological signaling may not receive benefits from this research.
What this research studies
This research focuses on understanding how localized kinase signaling in the brain influences learning and memory behaviors. Using advanced biosensors, the study aims to visualize and analyze the activity of key signaling pathways in targeted brain circuits. By examining these pathways in both normal and disease models, including those with learning/memory dysfunction and epilepsy, the research seeks to uncover the mechanisms behind behavioral outputs. Patients may benefit from insights gained about how these signaling processes can be targeted for therapeutic interventions.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for learning and memory disorders.
How similar studies have gone: Other research has shown promising results using similar biosensor technologies to study brain signaling, indicating potential for success in this approach.
Where this research is happening
-
Vanderbilt University
Nashville, United States Active
Researchers
- Principal investigator: Broadie, Kendal — Vanderbilt University
- Study coordinator: Broadie, Kendal
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.