NIH-funded research R01 grant

RSELVES Study: How older couples influence daily life and function with Alzheimer’s risk

Official title: The RSELVES Study: Remote Sensing of (older adult partners') Engagement in Life and Variability in Everyday Support

Funded at Vanderbilt University · NIH-11581025 · Data updated 2026-11-12

A study to understand how daily routines and support between older adults and their partners relate to the development of Alzheimer’s-related functional decline.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVanderbilt University
NIH-funded
Lab location1 site (Nashville, UNITED STATES)
Project startJanuary 15, 2023
Project endDecember 31, 2027
Funding year2026
Award (this year)$635,311
NIH project number7R01AG080644-05
Project IDNIH-11581025 on NIH RePORTER

Who could benefit from this research

Could help

Older adults in long-term partnerships (married or cohabiting) at high risk for Alzheimer’s disease.

Less likely to help

Individuals without an intimate partner or those not at elevated risk for Alzheimer’s may be less directly impacted by the findings.

What this research studies

This study follows older couples where one or both may be at risk for Alzheimer’s disease to see how their daily activities and mutual support change over time. Researchers will track routines, independence with daily tasks, and well-being to identify patterns that precede functional decline. The project uses remote sensing and other noninvasive methods to observe real-life daily life within the home setting. The goal is to uncover ways to slow decline by understanding how partner interactions influence function and cognition.

Why it matters

Potential benefit: If successful, findings could inform interventions that help couples maintain daily functioning longer.

How similar studies have gone: Previous research shows that daily activity engagement declines before dementia diagnosis, supporting the potential relevance of this dyadic approach.

Where this research is happening

  • Vanderbilt University
    Nashville, United States
    Active

Researchers

  • Principal investigator: Anderson, Lyndsey Medora — Vanderbilt University
  • Study coordinator: Anderson, Lyndsey Medora

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.