Investigating how potassium and sodium intake affects kidney function
Official title: Role of Kir4.1 in regulating NCC and ROMK in DCT
Funded at New York Medical College · NIH-11113800 · Data updated 2026-11-12
This study is looking at how certain proteins in your kidneys help manage potassium and sodium based on what you eat, so we can better understand how your diet affects kidney health over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York Medical College NIH-funded |
| Lab location | 1 site (Valhalla, United States) |
| Project start | September 1, 2022 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $663,882 |
| NIH project number | 5R01DK133220-04 |
| Project ID | NIH-11113800 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with chronic kidney disease or those experiencing issues related to potassium and sodium balance.
✕Less likely to help
Patients without any kidney-related issues or those not affected by dietary potassium or sodium levels may not benefit from this research.
What this research studies
This research explores the role of specific proteins in the kidney that help regulate how the body processes potassium and sodium based on dietary intake. It focuses on the distal convoluted tubule (DCT) of the kidney, examining how changes in potassium and sodium levels can influence kidney function and electrolyte balance. By understanding these mechanisms, the research aims to uncover how dietary habits impact kidney health over time, particularly in response to varying levels of these minerals.
Why it matters
Potential benefit: If successful, this research could lead to improved dietary recommendations and treatments for patients with chronic kidney disease.
How similar studies have gone: Previous research has shown promising results in understanding the role of dietary intake on kidney function, suggesting that this approach may yield valuable insights.
Where this research is happening
-
New York Medical College
Valhalla, United States Active
Researchers
- Principal investigator: Wang, Wenhui — New York Medical College
- Study coordinator: Wang, Wenhui
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.